Moroccan envoy sent by the King of Morocco to the Netherlands about 1591; subsequently acted as consul there; died at The Hague 1616. He proposed to the magistrates of Middleburg in Zealand to make that town an asylum for the Maranos, who would raise it to a considerable seaport. The clergy of the town were against the proposal, which fell through. Palache did much for the settlement of the Maranos in Amsterdam in 1593, and gained great favor with the stadholder. Prince Maurice of Orange attended Samuel's obsequies.
- De Barrios, Historia Universal Judaica, p. 20;
- Grätz, Gesch. ix. 478, 480;
- Koenen, Geschiedenis der Joden in Nederland, pp. 190 et seq.